Sirolimus anticorps

N° du produit ABIN1169577

Cet anticorps anti- est un anticorps Mouton Polyclonal détectant dans AP, ELISA et IA. Adapté pour Différentes espèces.

Aperçu rapide pour Sirolimus anticorps (ABIN1169577)

Antigène: Sirolimus

Reactivité: Différentes espèces

Hôte: Mouton

Clonalité: Polyclonal

Application: Affinity Purification (AP), ELISA, Immunoassay (IA)

Détail du produit

Fonction: Sirolimus

Sensibilité: 10ng/mL
Prednisolone produces 59% inhibition in a competitive ELISA employing Prednisolone polyclonal Antibody

Purification: Salt fractionation.

Immunogène: Sirolimus-BTG

Isotype: IgG

Information d'application

Indications d'application:

Application_Dilutions: 2.5 μg/mL

Tested_Applications: The antibody is suitable for the development of immunoassays or immunoaffinity purification columns.

Commentaires:

10 ng/mL Rapamycin (Sirolimus) produces 63 % inhibition in a competitive ELISA employing Sirolimus polyclonal antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 20 mM Phosphate, 150 mM Sodium Chloride. pH 7.4, 0.09 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Can be stored for up to 3 months at +2°C - +8°C. For long term storage, aliquot and store at ≤-20 °C. Avoid repeated freeze/thaw cycles. Product should be protected from light exposure.

Détail du antigène

Antigène: Sirolimus

Classe de substances: Chemical

Sujet: Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS) [1]. DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver [2]. DHEA in adults is present at plasma concentrations 100 to 500 times higher than those of testosterone. DHEA can be metabolized to androgens and/or estrogens in the prostate [3]. Hepatic metabolites include 16alpha-hydroxy-DHEA, 7alpha-hydroxy-DHEA, and 7-oxo-DHEA [4]. 7beta-OH-DHEA is a metabolite [5]. The major metabolite produced in humans is a mono-hydroxylated DHEA species [4]. Synthesis of a 7alpha-hydroxy-DHEA and 5-androstene-3beta, 17beta-diol occurs in the frontal cortex, hippocampus, aμgdala, cerebellum and striatum [6].